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DNA Replication using Bio Printer

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Bio printing is a subordinate of 3D printing, also known as additive manufacturing, focused on the creation of organs, DNA ,body parts and limbs compatible and functional enough to be fit for transplantation.  The main application of this under-research technology is to create and/or replicate living tissues which is achieved by creating layers of living cells. Bio printing is an emerging science which is still very much in its earliest stages and is yet to be commercially viable.

The idea of Bio printing is made possible by the advent of modern three dimensional printers. 3D (short for three dimensional) printing is the process of printing out three dimensional models and objects instead of the more traditional 2D printing on papers. 3D printers use computer controlled mechanism to create layers of material making up objects based on a 3D model. Bio printing is made possible by the fact that 3D printing can be done with any material or chemical such as plastics, metal or even living cells. Computers are at the heart of the 3D printing controlling and process, and are thus vitally important to Bio printing.

Process of DNA Replication

3D printing prints out objects based on a computer generated three dimensional models. For Bio printing, the models of DNA Replication, organs or limbs to be replicated can be easily scanned using CT or MRI scans and the printing would be done based on those models. The actual implementation of the printing mechanism varies between different manufacturers, some use a design similar to the traditional ink jet printers while some others have used six-axis printers which print multiple parts simultaneously. The anticipated outcome of the process is a useable and compatible human organ which can then be transplanted in the patient’s body.

Cells are used like ink droplets, and are injected at the correct points to replicate the model, controlled by the computer based on the model generated through the scans. The cells are fused together with hydrogel to make tissues, which constitutes as the building block of human body and can thus be used to recreate a body part.

Application of DNA Replication using Bio Printer

The aspired application of the Bio printing is to be able to commercially print body parts, limbs and organs to help disabled people out in the basis of DNA replication. This includes even the most complex organs like the heart. But the technology is still being researched and not at the stage to be used commercially. If sufficient advances are made in the technology, the need for organ donors would cease to exist and it would be a breakthrough in medical science. It will also eradicate a big problem in creation of artificial limbs like arm and legs.

The pioneers in bio printing are the people, firms and companies who are dedicated to researching, correcting and perfecting the process of bio printing. Bio printing is one of the most attractive researches in medical science and therefore many medical institutions and companies are working on it. The major pioneers of bio printing are following:

  • Makoto Nakamura –          A Japanese scientist
  • Organovo –          The leading company in bio printing
  • Envisionic Bioplotter –          Another major company in research of the subject
  • Tissue Engineering and Regenerative Medicine Lab at Columbia University

Benefits of DNA replications based on 3D bio printing

The benefits of rapid drugs discovery and early identification of toxicity issues have caught the attention of pharmaceutical companies .for instance orgnavo sign a collaborative research agreement with roche 1st year. While Murphy cannot describe scope of the work it is presumably to test compounds.

04-30-16

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